Thanks to new advancements in colonoscopy prep medicines, patients now have access to better-tasting, lower-volume, and easier-to-manage options. 

These innovations aim to make preparation more tolerable and effective, so you’re not only more comfortable, but also more likely to complete the prep properly.

In this article, we’ll walk you through the latest colonoscopy prep innovations, how they improve the experience, and what to consider if you’re preparing for your next screening.

Recent Advancements in Colonoscopy Prep Medicine

From low-volume drinks to easier-to-tolerate flavors and even pill-based options, today’s prep methods are designed with comfort and effectiveness in mind.

Here’s a look at the latest solutions making the process smoother for everyone.

Low-Volume Prep Solutions

Gone are the days when you had to drink a gallon of salty liquid. New formulations like Plenvu and CLENPIQ require far less volume, about 16 ounces per dose, and are just as effective. Plenvu, for example, offers a split-dose regimen with a fruitier flavor, while CLENPIQ is a ready-to-drink solution with no mixing required.

If you’re not sure how prep volume affects your experience, check out our Colonoscopy Prep Volume Guide to learn what’s right for you.

Improved Flavors and Formats

Many newer preps now include flavoring packets or come pre-flavored to reduce nausea and improve compliance. Options like Suprep and MoviPrep are commonly chosen for their improved taste and manageable volume. MoviPrep even allows for chilling or mixing with clear liquids to make the process easier to stomach.

Try these safe additives and flavor tips to improve the experience.

Extended Time Preps

Flexible timing options are another breakthrough. These allow patients to space out their prep over a longer period, such as doing part the evening before and part the morning of the procedure. This split-dose approach has been shown to result in better colon cleansing and less discomfort.

If you’re deciding between timing methods or prep types, see our breakdown on how to compare prep options.

Tablet-Based Preps

For those who can’t handle liquids well, tablet-based preps like Sutab are game changers. Rather than drinking liters of fluid, you take a series of pills with water. Some patients find this method easier to tolerate, although it still requires a commitment to consuming a specific amount of liquid to stay hydrated.

Updated Guidelines for Bowel Prep

The U.S. Multi-Society Task Force on Colorectal Cancer has refined its recommendations to reflect what works best for both patients and physicians. 

Two major updates stand out: a stronger emphasis on split-dose regimens and a preference for low-volume preparations. These updates have been shown to boost the effectiveness of cleansing and improve polyp detection, key factors for a successful colonoscopy.

In addition, new adjunctive strategies are being encouraged. This includes using simethicone, which can reduce bubbles and improve visibility during the procedure, as well as same-day salvage prep methods in case the initial prep wasn’t fully effective.

To help you prepare and stay ahead of any discomfort, here’s a guide on colonoscopy prep side effects to watch for, so you know what’s normal, and when to call your doctor.

Considerations Before Choosing a New Colonoscopy Prep

As promising as these new prep options sound, they’re not one-size-fits-all. Here’s what to keep in mind:

• Talk to Your Doctor First: Your provider will consider your medical history, current medications, and risk factors before recommending a prep option.
• Cost and Insurance: Some of the newer, more convenient preps may be more expensive. If you’re uninsured or have a high-deductible plan, ask about affordable programs like ColonoscopyAssist, which offer fixed-cost colonoscopy packages.
• Personal Preferences: Whether you prefer pills over liquids, or want a prep that lets you sleep through the night, discussing your preferences with your care team can help guide the best choice.

Final Thoughts

The world of colonoscopy prep has come a long way. Thanks to advancements in colonoscopy research and formulation, patients today have access to easier colonoscopy prep options that are more effective and far less stressful. 

Whether it’s a low-volume liquid, a flavored drink, or a tablet alternative, there’s likely a solution that fits your needs.

Disclaimer

Before making any decisions regarding anesthesia, sedation options, colonoscopies, or any medical procedure, always consult with your physician, anesthesiologist, or qualified healthcare provider. This article should not be used as a substitute for professional medical advice, diagnosis, or treatment.