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Colonoscopy Prep solutions typically fall into two categories: low-volume and high-volume. Both are designed to clean out the colon, but how they work, and how they feel, can be very different.
Today’s guide breaks down the pros, cons, and key differences to help you decide which colonoscopy prep is right for you.
What’s the Difference?
Colonoscopy prep solutions are classified by volume, how much liquid you need to drink.
- Low-volume preps typically involve drinking 2 to 3 liters of solution (often split into two doses).
- High-volume preps can require up to 4 liters of liquid, taken over several hours.
Both options aim to fully cleanse the colon, which is crucial for your doctor to get a clear view during the procedure.
Low-Volume Prep Solutions
Low-volume prep solutions have grown in popularity because of their ease of use and better taste. Popular options include Clenpiq, Suprep, and Plenvu.
These solutions are typically taken in two small doses and are more concentrated, so patients don’t have to drink as much.
| Pros | Cons |
|---|---|
| Easier to finish due to the smaller volume | These options require a prescription |
| Often flavored or ready-to-drink (no mixing required) | They tend to be more expensive, especially without insurance |
| Higher patient compliance and less discomfort | Not all options are suitable for patients with certain medical conditions |
A study, conducted in 2021, comparing MoviPrep (low-volume) to GoLYTELY (high-volume) found that 68.8% of patients rated MoviPrep as “easy” or “acceptable,” compared to only 43.3% for GoLYTELY.
Reference: Efficacy and tolerability of high and low-volume bowel preparation compared: A real-life single-blinded large-population study
High-Volume Prep Solutions
Traditional high-volume preps like GoLYTELY and Colyte are still widely used in medical settings. These solutions require you to drink up to a gallon (4 liters) of liquid, typically over several hours.
Why so much? The large volume helps to flush the colon thoroughly and steadily. It’s been the standard for years, especially in hospital environments.
| Pros | Cons |
|---|---|
| Time-tested and widely available | Taste and texture can be unpleasant |
| Often less expensive | Large volume may cause nausea, bloating, or trouble finishing the prep |
| May be covered more easily by insurance | Requires careful mixing and timing, which can be inconvenient |
According to a study published in the World Journal of Gastroenterology, the rate of colonoscopies conducted with inadequate bowel cleansing varies from 5% to 35%.
This suggests that a significant number of patients may struggle to complete the prescribed bowel prep regimen, potentially compromising the procedure’s effectiveness and increasing the likelihood of needing a repeat colonoscopy.
To help make your colonoscopy prep easier, The University of Chicago Medicine recommends chilling the solution and drinking it slowly (or through a straw) as it can help reduce discomfort.
How to Choose the Right Volume
When it comes to prep, there’s no one-size-fits-all answer. Your choice should be based on:
- How much liquid you can tolerate
- Any history of kidney issues or dehydration
- Budget and insurance coverage
- Doctor’s recommendation based on your health profile
If drinking large amounts sounds impossible, a low-volume option may be more manageable. On the other hand, if cost is a concern and you’re okay with the extra liquid, a high-volume solution may be more practical.
Either way, talk to your provider about what makes the most sense for you.
Affordable Options for All Prep Types
No matter which prep solution you and your doctor choose, ColonoscopyAssist is here to help make colonoscopies more accessible and affordable, especially for the uninsured or those with high deductibles.
Through a nationwide network of accredited providers, ColonoscopyAssist offers transparent pricing and support from start to finish.
Final Thoughts
Whether you go low-volume for comfort or high-volume for affordability, what matters most is following your doctor’s instructions to the letter.
A well-prepped colon leads to more accurate results, helping you catch any potential health issues early. Prioritize your comfort, but don’t skip the prep.
Disclaimer
Before making any decisions regarding anesthesia, sedation options, colonoscopies, or any medical procedure, always consult with your physician, anesthesiologist, or qualified healthcare provider. This article should not be used as a substitute for professional medical advice, diagnosis, or treatment.
